We are looking for highly motivated post-doctoral research associates with strong publication records to work in the Laboratory for Clinical Neuroscience at the Centre for Biomedical Technology, Universidad Politecnica de Madrid.
Job description: You will work on the European Research Council (ERC) Consolidator project awarded to Bryan Strange, director of the Laboratory for Clinical Neuroscience. This 5-year project, with 2 million euros of funding, is described here (http://www.thestrangelab.org/erc-cog-rememberex/). The successful applicants will form part of a multi-disciplinary team comprising neurosurgeons, neurologists, psychiatrists, psychologists and biomedical engineers.
Type of contract: Full-time. The initial contract will be made for 1 year (with an initial 6 month trial period) and is renewable for up to 5 years.
Start date: Summer 2019 (with some flexibility)
Send CV, motivation letter, and contact details of three academic referees to RememberEx@ctb.upm.es for the attention of Prof. Bryan Strange
Deadline: 31 May 2019
Required for the 3 positions:
A PhD in neuroscience, biomedical engineering, statistics, neurology, psychiatry, neuropsychology, or related field.
Fluent in English (written and spoken); Spanish is not required
Scripting languages (e.g. Matlab, Python, R)
Strong publication record
Desired for the 3 positions:
Knowledge of the basic and clinical neuroscience of learning, memory, emotion and responses to novelty
Demonstrated ability to secure research funding
Enthusiasm for communicating scientific advances
Specific requirements for each position:
Position 1. The successful candidate will be highly competent in the acquisition and analysis of intracranial electrophysiological local field potential recordings. We primarily use the Fieldtrip toolbox for human intracranial analyses, so experience with Fieldtrip (or SPM12) is desirable. Knowledge of measures of between-region connectivity is essential. A dataset of >30 patients with intracranial recordings during various memory tasks is already available. Additional recordings are on-going in Madrid and Zurich. The successful candidate will work on hippocampal responses to various types of salience, with an emphasis on hippocampal-cortical and hippocampal-amygdala coupling.
Position 2. The successful candidate will be expert in the acquisition and analysis of magnetoencephalography (MEG) recordings (the lab currently uses Fieldtrip and Brainstorm packages, primarily). Expertise in design and optimisation of cognitive tasks during MEG recordings is required. The successful candidate will lead the simultaneous acquisition of MEG and nucleus accumbens deep brain stimulation (DBS) in psychiatric patients using flexible head cast technology. Experience with EEG recordings is also desirable, as some DBS patients are also recorded from using a high density EEG system in the Hospital setting.
Position 3. The successful candidate will be expert in the acquisition and analysis of structural and functional MRI data using SPM, FSL, Freesurfer and/or Ants. Expertise in design and optimisation of cognitive tasks during fMRI recordings is required. The successful candidate will lead the functional MRI scanning of innovative tasks testing hypotheses generated from intracranial recordings. This research associate will also devise measurements of structural connectivity associated with memory effects observed in patients undergoing deep brain stimulation.
General responsibilities applicable to all Research Associate positions:
Help mentor graduate students in the lab
Attend weekly lab meetings
Coordinate your data acquisition between the lab and different Hospitals, both within Spain and abroad (UK and Switzerland). A project manager will assist you.
Present research findings at international conferences. Each position comes with a travel budget of 2000 euros per year for e.g. 2 European or 1 Intercontinental trip per year.
Internal Number: 1
About Laboratory for Clinical Neuroscience, Madrid
Our laboratory explores the cerebral basis of cognitive function in healthy people and in patients with neurological and psychiatric diseases. We are particularly interested in human memory formation and emotional processing.
We are based within the Centre for Biomedical Technology, Technical University of Madrid, and are affiliated to a number of clinical institutions (such as Hospital Clinico San Carlos, a central Madrid teaching Hospital), providing an interdisciplinary platform for clinical and cognitive neuroscience.
We employ a multimodal approach to the study of human memory and emotions, and are currently conducting research using:
Intracranial recordings in humans
Functional Magnetic Resonance Imaging (fMRI)
Transcranial magnetic stimulation (TMS)
Cognitive effects of deep-brain stimulation (DBS)
As part of a major research focus in understanding memory decline in aging and dementia, we form the Neuroimaging Department of the Spanish Research Centre for Neurological Diseases. At this site we have:
A research-dedicated MRI facility attached to a 156-bed residence for patients wit...h Alzheimer’s disease.
A brain-bank providing post-mortem histopathological confirmation of dementia diagnosis for patients scanned pre-mortem.
A 5-year longitudinal study (currently in year 5) of 1200 healthy elderly individuals (aged 70-85). At each yearly visit, volunteers undergo detailed neuropsychological and clinical evaluation, serum biochemistry analysis, as well as a comprehensive MRI protocol, with genetic data acquired on visit 1.
Ex-vivo MRI scanning.